Schizo - obsessive disorder - separate clinical entity or elusive comorbidity? - a systematic review

Schizo - obsessive disorder - separate clinical entity or elusive comorbidity? - a systematic review

Blog Article

Introduction In some clinical scenarios obsessive and delusive symptoms exhibit several similarities, making it challenging to differentiate between schizophrenia spectrum disorder (SSD) and obsessive-compulsive disorder (OCD).There are moondrop quarks numerous reports of patients suffering from those disorders and manifesting both psychotic and obsession-like features, which makes accurate distinction even more complicated.We found several conflicting theories attempting to elucidate this overlap, one being the existence of the separate clinical entity - schizo-obsessive disorder.Objectives The aim of this study is to consolidate current knowledge, synthesize existing theories and explore diagnostic implications.

Methods We conducted a systematic literature review following the PRISMA protocol, we scrutinized studies addressing obsession-like symptoms in SSD, psychotic symptoms in OCD, and comorbidity of those disorders.We included peer-reviewed non-interventional studies published in English and Polish from 2013 onwards.The search was performed in the following medical databases: PubMed, Science Direct, Scopus, and Web of Science.Synthesis utilized a narrative approach product due to diverse study designs, outcomes and observational nature of the collected data.

Results We identified several dozen articles, which revealed a range of diverse findings, often inconclusive, and occasionally conflicting, Although, the collected data indicate the schizo-obsessive spectrum exhibits clinical relevance.Conclusions The ambiguity in results emphasizes the necessity for further investigations into pathomechanism of schizophrenia and OCD.Future research, particularly involving children and adolescents, should strive for a comprehensive understanding of the nuanced manifestations of obsessive-like and psychotic symptoms in both disorders, aiding in refining diagnostic criteria and developing effective intervention strategies.Disclosure of Interest None Declared.